De-Xiang Xu Selected Research

Necrosis

5/2024	m6A-methylated Lonp1 drives mitochondrial proteostasis stress to induce testicular pyroptosis upon environmental cadmium.
8/2021	Vitamin D deficiency exacerbates hepatic oxidative stress and inflammation during acetaminophen-induced acute liver injury in mice.
1/2019	Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice.
1/2013	Phenylbutyric acid protects against carbon tetrachloride-induced hepatic fibrogenesis in mice.
5/2011	The protective effects of ursodeoxycholic acid on isoniazid plus rifampicin induced liver injury in mice.
3/2008	Differential effects of pyrrolidine dithiocarbamate on TNF-alpha-mediated liver injury in two different models of fulminant hepatitis.
3/2006	A dual effect of N-acetylcysteine on acute ethanol-induced liver damage in mice.

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De-Xiang Xu Research Topics

Disease

37	Fetal Growth Retardation (Intrauterine Growth Retardation) 01/2024 - 05/2006
21	Inflammation (Inflammations) 12/2023 - 05/2011
15	Fetal Death 04/2019 - 12/2005
12	Vitamin D Deficiency 12/2023 - 05/2015
8	Chronic Obstructive Pulmonary Disease (COPD) 06/2023 - 01/2021
7	Pulmonary Fibrosis (Fibrosing Alveolitis) 05/2024 - 01/2014
7	Necrosis 05/2024 - 03/2006
7	Fibrosis (Cirrhosis) 05/2021 - 01/2013
7	Fetal Weight 01/2021 - 01/2006
6	Prostatic Neoplasms (Prostate Cancer) 01/2023 - 01/2017
6	Neural Tube Defects (Exencephaly) 03/2016 - 01/2013
5	Acute Lung Injury 12/2022 - 01/2016
5	Acute Kidney Injury (Acute Renal Failure) 06/2022 - 08/2015
4	Obesity 02/2024 - 06/2015
4	Pneumonia (Pneumonitis) 01/2023 - 01/2016
4	Sepsis (Septicemia) 06/2022 - 08/2015
4	Insulin Resistance 10/2018 - 01/2014
4	Non-alcoholic Fatty Liver Disease 02/2017 - 11/2011
3	Male Infertility (Male Sterility) 02/2024 - 12/2011
3	Glucose Intolerance 01/2022 - 10/2018
3	Renal Cell Carcinoma (Grawitz Tumor) 01/2020 - 10/2019
3	Liver Cirrhosis (Hepatic Cirrhosis) 12/2019 - 02/2017
3	Acute Liver Failure (Fulminant Hepatic Failure) 05/2019 - 01/2012
3	Congenital Abnormalities (Deformity) 09/2016 - 03/2012
3	Premature Obstetric Labor (Premature Labor) 05/2007 - 01/2006
2	Overweight 02/2024 - 06/2015
2	Dysbiosis 05/2023 - 01/2021
2	Asthma (Bronchial Asthma) 04/2023 - 03/2020
2	Hyperplasia 12/2022 - 03/2020
2	Infections 06/2020 - 02/2010
2	Cholestasis 01/2019 - 10/2009
2	Premature Birth (Birth, Premature) 09/2016 - 03/2016
2	Fetal Resorption 01/2014 - 05/2008
2	Teratogenesis 01/2014 - 05/2008
1	Autistic Disorder (Autism) 05/2024

Drug/Important Bio-Agent (IBA)

34	LipopolysaccharidesIBA 11/2023 - 12/2005
21	CadmiumIBA 05/2024 - 12/2011
11	Vitamin D FDA LinkGeneric 01/2023 - 05/2015
10	CytokinesIBA 12/2022 - 01/2016
9	Cholecalciferol (Vitamin D3)FDA Link 12/2023 - 05/2015
9	MelatoninIBA 11/2023 - 01/2006
8	AntioxidantsIBA 02/2024 - 03/2012
7	Calcitriol (Calcijex)FDA LinkGeneric 12/2023 - 01/2016
7	obeticholic acidIBA 12/2019 - 12/2016
6	Folic Acid (Vitamin M)FDA LinkGeneric 01/2023 - 01/2013
6	Bleomycin (Blenoxane)FDA LinkGeneric 12/2022 - 01/2014
6	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2022 - 12/2006
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021 - 05/2006
5	Diethylhexyl Phthalate (DEHP)IBA 05/2023 - 01/2017
5	ArsenicIBA 01/2023 - 01/2021
5	EnzymesIBA 01/2023 - 06/2015
5	LipidsIBA 01/2022 - 08/2012
5	hydroxide ionIBA 01/2021 - 02/2017
4	Acetylcysteine (Siran)FDA LinkGeneric 01/2022 - 12/2005
4	Acetaminophen (Paracetamol)FDA LinkGeneric 08/2021 - 01/2012
4	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2020 - 06/2015
4	Carbon Tetrachloride (Tetrachloromethane)IBA 12/2019 - 01/2013
4	ZincIBA 03/2016 - 07/2012
3	1-nitropyreneIBA 05/2024 - 03/2020
3	DNA (Deoxyribonucleic Acid)IBA 05/2024 - 05/2003
3	Progesterone FDA LinkGeneric 01/2024 - 01/2020
3	Environmental Pollutants (Pollutants, Environmental)IBA 01/2022 - 01/2021
3	CollagenIBA 01/2022 - 01/2018
3	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2019
3	fenvalerateIBA 10/2021 - 01/2017
3	ChemokinesIBA 08/2021 - 11/2018
3	Calcitriol Receptors (Calcitriol Receptor)IBA 01/2021 - 06/2015
3	NF-kappa B (NF-kB)IBA 01/2021 - 06/2015
3	phthalic acid (phthalate)IBA 09/2020 - 01/2017
3	Messenger RNA (mRNA)IBA 03/2020 - 01/2018
3	Interleukin-6 (Interleukin 6)IBA 10/2019 - 01/2018
3	Rifampin (Rifampicin)FDA LinkGeneric 01/2016 - 10/2009
2	Benzo(a)pyreneIBA 05/2024 - 01/2022
2	AcidsIBA 11/2023 - 01/2015
2	OvalbuminIBA 04/2023 - 12/2022
2	CreatinineIBA 01/2023 - 09/2020
2	CateninsIBA 01/2023 - 01/2020
2	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2021
2	Free RadicalsIBA 07/2021 - 12/2006
2	indium-bleomycinIBA 05/2021 - 11/2019
2	Hormones (Hormone)IBA 01/2021 - 04/2019
2	SteroidsIBA 01/2021 - 04/2019
2	GlucocorticoidsIBA 09/2020 - 01/2019
2	Bile Acids and Salts (Bile Acids)IBA 06/2020 - 01/2019
2	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2020 - 11/2018
2	C-Reactive ProteinIBA 11/2019 - 03/2017
2	Fatty Acids (Saturated Fatty Acids)IBA 10/2019 - 06/2015
2	Glutathione (Reduced Glutathione)IBA 01/2019 - 12/2006
2	Rosiglitazone (Avandia)FDA Link 01/2019 - 03/2016
2	Thyroid Hormone Receptors (Thyroid Hormone Receptor)IBA 09/2018 - 01/2017
2	InterleukinsIBA 03/2017 - 08/2007
2	Interleukin-8 (Interleukin 8)IBA 03/2017 - 02/2017
2	Apoptosis Inducing FactorIBA 03/2014 - 01/2012
2	Alanine Transaminase (SGPT)IBA 03/2008 - 07/2007
1	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amideIBA 05/2024
1	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxideIBA 05/2024
1	N-methyladenosineIBA 02/2024
1	TEMPOIBA 02/2024
1	6-methyladenineIBA 02/2024
1	Dextran SulfateIBA 12/2023